Paperpile

Referenced Papers (6)

Learning the protein language: Evolution, structure, and function

Tristan Bepler, Bonnie Berger

Cell Syst., 2021

"This paper is cited as an example of using representation learning and unsupervised models for density estimation on large-scale protein databases."

Referenced at: 05:49

Illuminating protein space with a programmable generative model

John B Ingraham, Max Baranov, Zak Costello, Karl W Barber, Wujie Wang, Ahmed Ismail

Nature, 2023

"Cited as an example of the latest trend in using generative models, specifically diffusion models, for predicting protein backbone structures."

Referenced at: 07:50

Generative models for protein structures and sequences

Chloe Hsu, Clara Fannjiang, Jennifer Listgarten

Nat. Biotechnol., 2024

"The speaker cites this primer, which she co-authored, as a resource for the audience to learn more about generative models for protein structures and sequences."

Referenced at: 08:34

Automatic chemical design using a data-driven continuous representation of molecules

Rafael Gómez-Bombarelli, Jennifer N Wei, David Duvenaud, José Miguel Hernández-Lobato, Benjamín Sánchez-Lengeling, Dennis Sheberla

ACS Cent. Sci., 2018

"This is one of several papers cited from the speaker's group that explores the fundamental tension between extrapolation and trustworthiness in machine learning-based protein design."

Referenced at: 14:24

Unlocking guidance for discrete state-space diffusion and flow models

Hunter Nisonoff, Junhao Xiong, Stephan Allenspach, Jennifer Listgarten

arXiv [cs.LG], 2024

"This work from the speaker's lab is presented as a method for providing property guidance for diffusion and flow matching on discrete spaces."

Referenced at: 16:54

Optimal trade-off control in machine learning-based library design, with application to adeno-associated virus (AAV) for gene therapy

Danqing Zhu, David H Brookes, Akosua Busia, Ana Carneiro, Clara Fannjiang, Galina Popova

Sci. Adv., 2024

"This paper describes the AAV library design project detailed in the talk, which combines various machine learning techniques to create more effective libraries for directed evolution."

Referenced at: 16:54